Ludwig-Maximilians-Universität München, Biomedical Center, Großhaderner Str. 9, 82152 Planegg DE

www.physiolchemie.abi.med.uni-muenchen.de

Spletter Lab Webpage

Alternative splicing and RNA regulation in muscle development

Want to find out more? Check out Dr. Spletter's 2018 TEDxTUM talk on "What flies can teach us about muscle disease"

TEDxTUM talk

About Us

Mission

Recent Events

Projects

Our vision is to provide a more complete understanding of the regulation and function of RNA processing in muscle development. Along the way, we are identifying which proteins can bind to and regulate RNA, working to gain a deeper understanding of muscle development itself and investigating the function of alternatively spliced isoforms during myogenesis.

Research

Projects

Recent Events

Projects

Project 1: Doctoral candidate Elena Nikonova is investigating potential isoform-specific functions of the RNA binding proteins Bruno1 and Rbfox1.

Project 2: Doctoral candidate Shao-Yen Kao is characterizing the phenotype of U2 spliceosome component Scaf6/CHERP in muscle.

Project 3: Medical doctor candidate Jakob Heemken is studying the function of m6A modification enzyme Mettl3 in muscle.

Project Details

Recent Events

07.Jan 2022 - New manuscript published in Life Science Alliance: https://doi.org/10.26508/lsa.202101342
22.Sept 2021 - New manuscript published in Cells: https://doi.org/10.3390/cells10102505
11.May 2021 - New pre-print posted: https://doi.org/10.1101/2021.05.09.443278

Spletter Lab Webpage

Alternative splicing and RNA regulation in muscle development

Check out our video protocol on IFM dissection!

About Us

Mission

Recent Events

Projects

Projects

Recent Events

Projects

Recent Events

Recent Events

Recent Events

Social